…. and it’s good news!!
My TNF levels have come down from 33 to 25 – within normal range – which means that I don’t have to have any more Humira injections!!! I’m so bloody HAPPY!!!!
This is brilliant news, as it means that we can now move to phase 2 of the treatment – and we can start trying again when I ovulate NEXT WEEK!!!! AAAAAAARGGGH!!!!
I’m over the moon that I don’t need any more injections. They were painful and made me feel exhausted, with a sore chest and a bad cold, so I’m really glad that they’re over. The effects of the Humira will last for about 9 months, so if I’m not pregnant by then i’ll have to have my levels tested again and if they’ve gone up then i’ll need more injections, but i’ll worry about that closer to the time (and hopefully I might be pregnant by then!).
I was so scared to let myself hope that this might be the outcome, as my default setting with all things fertility is negative, but I’m so happy that we’ve had this bit of good news. I’m also delighted that we can start trying again! Its been 6 months since we lost the third baby, so we’re both ready to get moving. Even if it takes us a while, at least we’re in with a shot each month, rather than just waiting and waiting like we have been. But I’m really glad that we’ve taken this time to have the laparoscopy, meet the specialist and start the treatment plan – it feels as though we’re doing all we can to have the best chance of keeping the next baby. Who knows how it will all go, but we’re doing our best.
The doc asked how I was feeling on all the drugs, and I told him that the metformin in making me feel sick pretty much all of the time, and that I’m only able to eat three small meals a day as the thought of most food just makes me feel sick. Ive lost a bit of weight because of this, and most of my friends have asked for some of it to help them shift the pounds – ha!! The doc said that because I’m small (I’m 5’4” and about 123lbs) that I can either try having one a day with breakfast, then two with dinner, so I don’t feel sick all day, or I can drop the dose down to 2 a day, rather than 3, which I’m really pleased about. I took 2 a day when I fell pregnant last time and it gave me 32 days cycles, which would still be great, even if its not 28 days like this last cycle has been. I’d trade a few extra days waiting if it meant I could eat normally and not feel sick 24/7!! I think i’ll try the new dosage (1, then 2 at dinner) and see how I get on with that. If this still no good, i’ll just drop it down to 2 a day.
So, here’s the plan now:
– I keep on the metformin, baby aspirin, Vitamin D and pregnancy vitamins with Omega 3, and start getting busy with my husband early next week!!
– On the day I ovulate next week, I start taking 25mg of steroids, then take one a day for 10 days. On the 10/11th day after ovulation, I take an early pregnancy test. If its positive, I keep taking the steroids and call the doc to arrange and intralipid infusion asap. This will help to coat the Natural Killer Cells and hopefully stop them from attacking the baby. I also start on progesterone pessaries.
– If it’s negative, I stop taking the steroids, wait a couple of days, then test again. If it’s then positive, see above. If it’s still negative, I just wait till I get my period as normal. I told the doc that I got all three positive pregnancy tests at 12 days past ovulation. He said that if you’re not pregnant, if you keep taking the steroids then it will delay you getting your period, which is agony when you think you might be pregnant. He’s tested it, and the best day to stop is 10 days in his opinion. If you then get a positive test, a couple of days being off the steroids won’t affect the chances as they will still be in your bloodstream, so you start taking them again.
– If I do get my period, I then start on Letrozole on day 2 of my period, to stimulate ovulation. I then arrange for a scan to see if i’m about to ovulate, and may need an injection of Ovitrelle to trigger ovulation. Then the same as above, get busy, start steroids, wait 10 days etc…
As usual, a lot to take in, but the bottom line is that we can start trying and that’s BRILLIANT!!
The doc has said that the steroids should be taken first thing in the morning, as they can make it difficult for you to sleep as you have a lot more energy. For the last 5 weeks I’ve had absolutely zero energy and felt like sh*t most of the time, so it’ll be a strange change to suddenly be bouncing around!!! He’s recommended going to the gym after work, so that I tire myself out and can then sleep each night. Im a bit nervous about not being able to sleep, as I’m not someone who functions well if I’m shattered, but I guess ill just have to see how it goes. Im only on a low dose, so I’m hoping that I manage ok.
I asked the doc what happens if I fall pregnant and then am really sick with morning sickness. He said that the steroids take away any sickness which you have, so that shouldn’t be a problem. Apparently they are used as a last resort with women who are suffering from extreme morning sickness in pregnancy, so thats a funny coincidence I guess!!
So thats me for now. Im exhausted today from the nerves and anticipation of the results, so I’m looking forward to a good sleep and hopefully less sickness with the change in the metformin. I am nervous about trying again, but you have to be in it to win it as they say, so we just have to try and hope for the best.
I’ll let you know how I get on with the steroids, and can’t believe i’ll be back on the two week wait in the next couple of weeks!!